Monday, 27 April 2020

TNMSC & MGM | 25-50% of the people infected with COVID-19 reported

TNMSC & MGM” | 25-50% of the people infected with COVID-19 reported to develop symptoms

25-50% of the people infected with COVID-19 reported to develop symptoms of Acute Kidney Injury (AKI). A few patients even developed Acute Kidney Injury (AKI), a condition known to impact survival of patients. Also, a recent report of the International Society of Nephrology (ISN) reveals that of the people infected with COVID-19, 25-50% of them were seen with Kidney abnormalities, which manifested as a substantial leak of protein and blood in urine, resulting in the development of AKI in close to 15% patients, hinting that COVID-19 also attacks the kidney

Dr. Suresh Rao, Intensivist, MGM, Chennai says “Effect on the kidney is secondary to hypoxia or cytokines released by the covid19. It is generally perceived that COVID-19 types of viruses are borne from respiratory systems — Lungs, but a growing body of evidence shows that COVID-19 also attacks the kidneys either directly or mediated by excessive immune response seen in severe COVID-19 patients and not just the lungs. As per earlier reports of SARS and MERS-CoV infections, Acute Kidney Injury (AKI) had developed in 5 to 15 per cent cases, but about 60 to 90 per cent of those cases reported mortality. While the preliminary reports of COVID-19 patients suggested a lower incidence (3 to 9 per cent) of AKI, the later reports indicated a higher frequency of kidney abnormalities. A study of 59 patients with COVID-19 found that about two-thirds of patients developed a massive leak of protein in urine during their stay in hospital”,

Dr. NGK Gopal Nephrologist, TNMSC, Chennai says “Previous studies show that CRRT had been successfully applied in the treatment of SARS and MERS illnesses related to previously known coronaviruses, which also manifested as respiratory illnesses.  At relatively higher doses, it can help clear the immune toxins, thus suggesting CRRT may play a role in patients with COVID-19 with AKI or high immune toxin load”

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